Lymphatic vessels in human sural nerve: immunohistochemical detection by D2-40.

نویسندگان

  • N Volpi
  • M Aglianò
  • L Massai
  • C Alessandrini
  • S Rossi
  • A M Pucci
  • G Grasso
چکیده

Lymphatics were detected in the epineurium of the human sural nerve by D-240 immunostaining and confirmed by ultrastructural examination.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Lymphatic marker podoplanin/D2-40 in human advanced cirrhotic liver- Re-evaluations of microlymphatic abnormalities

BACKGROUND From the morphological appearance, it was impossible to distinguish terminal portal venules from small lymphatic vessels in the portal tract even using histochemical microscopic techniques. Recently, D2-40 was found to be expressed at a high level in lymphatic endothelial cells (LECs). This study was undertaken to elucidate hepatic lymphatic vessels during progression of cirrhosis by...

متن کامل

Clinical Significance of Lymphatic Microvessel Density and D2-40 Immunohistochemical Expression in Ovarian Cancer

Introduction: Lymphangiogenesis is the process of new lymphatic vessels formation from preexisting postcapillary venules. Although this process was extensively investigated in a large variety of human tumors, few data are available about the clinical significance of lymphatic vessels in ovarian cancer. The ovarian cancer is often characterized by an unpredictable behavior and there is a lack of...

متن کامل

Identification of Lymphatics within the Colonic Lamina Propria in Inflammation and Neoplasia Using the Monoclonal Antibody D2-40

CONTEXT Lymphatic vessels are believed to be absent in the colon above the level of the mucularis mucosae. However, in our experience, lymphatic vessels are sometimes identifiable within the lamina propria in the setting of inflammation and neoplasia. OBJECTIVE We sought to assess the presence of lymphatics within the colonic lamina propria in neoplastic and inflammatory conditions using the ...

متن کامل

Detection of lymphatic invasion in primary melanoma with monoclonal antibody D2-40: a new selective immunohistochemical marker of lymphatic endothelium.

OBJECTIVES To identify the presence of lymphatic invasion in primary cutaneous melanoma using monoclonal antibody D2-40, a marker of lymphatic endothelium, and to correlate the presence of lymphatic invasion with other clinicopathologic characteristics of the tumors. DESIGN Retrospective melanoma case series study comparing conventional hematoxylin-eosin staining with D2-40 immunostaining for...

متن کامل

The lymphatic infiltration identified by D2-40 monoclonal antibody predicts lymph node metastasis in submucosal invasive colorectal cancer.

BACKGROUND AND STUDY AIMS Lymphatic infiltration has been recognized as a significant risk factor for lymph node metastasis of submucosal invasive colorectal cancer (SICC), but it is difficult to detect microscopically on hematoxylin and eosin (H&E)-stained slides. We therefore identified lymphatic infiltration of tumor cells with D2-40 monoclonal antibody, which reacts specifically against the...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Lymphology

دوره 39 4  شماره 

صفحات  -

تاریخ انتشار 2006